Health
Protein ADAMTSL4 Identified as a Driver of Cancer-Related Muscle Wasting
A study published in Cancer Discovery on September 1, 2026, identifies the protein ADAMTSL4 as a tumor-secreted factor that triggers muscle and fat loss by activating latent TGF-β1. This discovery suggests a potential new therapeutic target for cancer cachexia, a condition for which no global standard treatment currently exists.