#cancer

Protein ADAMTSL4 Identified as a Driver of Cancer-Related Muscle Wasting

A study published in Cancer Discovery on September 1, 2026, identifies the protein ADAMTSL4 as a tumor-secreted factor that triggers muscle and fat loss by activating latent TGF-β1. This discovery suggests a potential new therapeutic target for cancer cachexia, a condition for which no global standard treatment currently exists.

Health Desk 3m ago

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Personalized mRNA Vaccine Passes Phase 3 Milestone for Melanoma Treatment

Moderna and Merck announced on August 19, 2026, that their personalized mRNA cancer vaccine, intismeran autogene, has successfully met its primary endpoints in a 1,137-patient Phase 3 clinical trial. The therapy significantly reduces the risk of recurrence and distant metastasis in patients with completely resected stage IIB-IV melanoma.

Health Desk 2h ago